Afuco™ Anti-Human IL22RA ADCC Recombinant Antibody (ARGX-112), ADCC Enhanced (CAT#: AFC-401CL)
Anti-IL22RA ADCC Enhanced Antibody (ARGX-112) is an ADCC enhanced antibody produced by our Afuco™ platform. ARGX-112 is a novel, fully human antibody neutralizing both IL20 and IL22 signaling through blockade of their common receptor, IL22R, with low picomolar potency. IL20 and IL22 are involved in proliferation and differentiation of keratinocytes (skin cells) and when over-expressed, are implicated in autoimmune diseases of the skin, including atopic dermatitis, psoriasis and pustular psoriasis. ARGX-112 has been shown to be highly effective in several preclinical models of chronic skin inflammation.
Specific Inquiry
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Autoimmune Diseases
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- IL22RA; Interleukin 22RA; IL22RA1; IL22RA2
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-563 | Recombinant Anti-IL-22RA Antibody | ELISA, WB, Dot, FuncS | IgG |
| MHH-563 | Recombinant Human Anti-IL-22RA Antibody | WB, IP, FuncS | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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