This product is a recombinant human anti-influenza A virus hemagglutinin H2 monoclonal antibody. 8F8 specifically binds to HA and can be potentially usd in the treatment of influenza virus infection.
Figure 1. Binding of stalk-reactive antibodies to recombinant JAP57 (H2) and VN04 (H5) HAs.
Binding of head-reactive antibody 8F8 and H2 antiserum to recombinant soluble JAP57 HA without (w/o T4 trim. domain, black lines) or with (w/T4 trim. domain, red line) trimerization domain.
Krammer, F., Margine, I., Tan, G. S., Pica, N., Krause, J. C., & Palese, P. (2012). A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substrates. PloS one, 7(8), e43603.
Figure 1 Binding of stalk-reactive antibodies to recombinant JAP57 (H2) and VN04 (H5) HAs.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-204LC-F(E) | Anti-Influenza A Virus Hemagglutinin H2 HA Recombinant Antibody Fab Fragment (25F7) | ELISA | Human antibody |
MRO-205LC-F(E) | Anti-Influenza A Virus Hemagglutinin H2 HA Recombinant Antibody Fab Fragment (8F8) | ELISA | Human antibody |
MRO-206LC-F(E) | Anti-Influenza A Virus Hemagglutinin H2 HA Recombinant Antibody Fab Fragment (18G6) | ELISA | Human antibody |
MRO-209LC-F(E) | Anti-Influenza A Virus Hemagglutinin H2 HA Recombinant Antibody Fab Fragment (8M2) | ELISA | Human antibody |
MRO-210LC-F(E) | Anti-Influenza A Virus Hemagglutinin H2 HA Recombinant Antibody Fab Fragment (2G1) | ELISA | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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