Afuco™ Anti-Human TNFSF9 ADCC Recombinant Antibody (PF-05082566), ADCC Enhanced
CAT#: AFC-618CL
Anti-TNFSF9 ADCC Enhanced Antibody (PF-05082566) is an ADCC enhanced antibody produced by our Afuco™ platform. PF-05082566 is a fully human IgG2 that binds to the extracellular domain of human 4-1BB with high affinity and specificity. In preclinical studies, this agonist antibody demonstrated its ability to activate NF-κB and induce downstream cytokine production, promote leukocyte proliferation, and inhibit tumor growth in a human PBMC xenograft tumor model. The mechanism of action and robust anti-tumor efficacy of PF-05082566 support its clinical development for the treatment of a broad spectrum of human malignancies.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SiHa
Immunofluorescent staining of human cell line SiHa shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59857/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HMC-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125657-TNFSF9
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- FC, Activ, FuncS
- Related Disease
- Cancer
Product Property
- Purity
- 95% by HPLC
- Storage
- Store at -20°C. Open under aseptic conditions.
Applications
- Application Notes
- The antibody was validated for Flow Cytometry, Activation, Function Assay. For details, refer to Published Data.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "TNFSF9"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1844z | Mouse Anti-TNFSF9 Recombinant Antibody (clone 15H10) | ELISA, WB | Mouse IgG1 |
| MOB-2095CT | Recombinant Mouse anti-Human TNFSF9 Monoclonal antibody (EML2043) | WB | |
| HPAB-0247-CN | Mouse Anti-TNFSF9 Recombinant Antibody (clone SC113.57) | ELISA, FC | Mouse IgG1 |
| HPAB-0248-CN | Mouse Anti-TNFSF9 Recombinant Antibody (clone SC113.18) | ELISA, FC | Mouse IgG1 |
| HPAB-0249-CN | Human Anti-TNFSF9 Recombinant Antibody (clone hSC113.57) | ELISA, FC | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-644CL | Human Anti-TNFSF9 Recombinant Antibody (TAB-644CL) | Inhib, FuncS | Human IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2207CQ | Rat Anti-Tnfsf9 Recombinant Antibody (NEUT-2207CQ) | Block, FC | Rat IgG2 |
| NEUT-2208CQ | Rat Anti-Tnfsf9 Recombinant Antibody (clone TKS-1) | Block, FC | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3623 | Rabbit Anti-TNFSF9 Recombinant Antibody (clone DS3623AB) | WB, IP, IHC | Rabbit IgG |
| MOR-3624 | Rabbit Anti-Tnfsf9 Recombinant Antibody (clone DS3624AB), FITC | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0247-CN-S(P) | Mouse Anti-TNFSF9 Recombinant Antibody (clone SC113.57); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0248-CN-S(P) | Mouse Anti-TNFSF9 Recombinant Antibody (clone SC113.18); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0249-CN-S(P) | Human Anti-TNFSF9 Recombinant Antibody (clone hSC113.57); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0250-CN-S(P) | Human Anti-TNFSF9 Recombinant Antibody (clone hSC113.18); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0002-LS-S(P) | Human Anti-TNFSF9 Recombinant Antibody (clone hSC113.118); scFv Fragment | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0247-CN-F(E) | Mouse Anti-TNFSF9 Recombinant Antibody (clone SC113.57); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0248-CN-F(E) | Mouse Anti-TNFSF9 Recombinant Antibody (clone SC113.18); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0249-CN-F(E) | Human Anti-TNFSF9 Recombinant Antibody (clone hSC113.57); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0250-CN-F(E) | Human Anti-TNFSF9 Recombinant Antibody (clone hSC113.18); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0251-CN-F(E) | Human Anti-TNFSF9 Recombinant Antibody (clone cSC113.57); Fab Fragment | ELISA, FC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7398 | Anti-Mouse TNFSF9 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC348 | SmartAb™ Recombinant Anti-TNFSF9 pH-dependent Antibody (VS-0825-YC348) | Inhibition | Human IgG2 |
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