Recombinant Mouse Anti-WNV ED3 Antibody (E16) (CAT#: PABC-243)
Recombinant Mouse Antibody (E16) is capable of binding to WNV ED3, expressed in Chinese Hamster Ovary cells (CHO). The E16 antibody Fab fragment engages 16 residues positioned on four loops of DIII, a consensus neutralizing epitope sequence conserved in West Nile virus and distinct in other flaviviruses. The E16 epitope protrudes from the surface of mature virions in three distinct environments, and docking studies predict Fab binding will leave five-fold clustered epitopes exposed. E16 inhibits infection primarily at a step after viral attachment, potentially by blocking envelope glycoprotein conformational changes.
Specific Inquiry
Specifications
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native WNV ED3
- Species Reactivity
- WNV
- Clone
- E16
- Applications
- Can be useful in applications such as: Neutralization
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- Envelope protein; ED3; WNV
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-301 | Recombinant Anti-ED3 Antibody | ELISA, IP, FuncS | IgG |
| PABC-147 | Recombinant Mouse Anti-DENV-4 EDIII Antibody (2D73) | ELISA | IgG |
| PABC-148 | Recombinant Mouse Anti-DENV-4 EDIII Antibody (3E31) | ELISA | IgG |
| PABC-149 | Recombinant Mouse Anti-DENV-4 EDIII Antibody (2H12) | ELISA | IgG |
| PABC-150 | Recombinant Mouse Anti-DENV-3 EDIII Antibody (2H12) | ELISA | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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