Recombinant Anti-EGFR × Anti-FcγRI Bispecific Antibody (Fab2) (CAT#: FAB-L007)

Recombinant Anti-EGFR & Anti-FcγRI Bispecific Antibody (Fab2) is composed of the Fab of the anti-EGFR monoclonal antibody and Fab of an antibody specific for FcγRI. A linker is added between the two Fab. The bispecific antibody is somewhat smaller than a whole IgG and therefore it can be cleared from the blood naturally at a faster rate. This BsAb can retarget of immune cells to tumor cells. It was designed for the treatment of colon and pancreatic cancers.

Specific Inquiry
  • Size:
  • Conjugation:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Target
  • EGFR & FcγRI
  • Type
  • Fab2
  • Species Reactivity
  • Human
  • Target 1
  • EGFR
  • Host Species 1
  • Human
  • Target 2
  • FcγRI
  • Host Species 2
  • Human
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Colon and pancreatic cancers

Target

  • Target 1
  • EGFR
  • Alternative Names
  • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1;
  • Target 2
  • FcγRI
  • Alternative Names
  • FCGR1A; Fc fragment of IgG, high affinity Ia, receptor (CD64); CD64; FCRI; CD64A; IGFR1; high affinity immunoglobulin gamma Fc receptor I; fcgammaRIa; Fc-gamma RI; fc-gamma RIA; Fc gamma receptor; IgG Fc receptor I; Fc-gamma receptor I A1; Fc fragment of IgG, high affinity Ia, receptor for (CD64)

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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