Anti-Human CD40 Recombinant Antibody (Selicrelumab) (CAT#: TAB-470CQ)
Recombinant monoclonal antibody to CD40. Selicrelumab is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Anti-Human CD40 Recombinant Antibody (Selicrelumab) (TAB-470CQ) in SDS-PAGE
SDS-PAGE analysis of TAB-470CQ in non-reduced (Lane 1) and reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result, different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
The purity of TAB-470CQ was greater than 95% as determined by SDS-PAGE.
Figure 2 Anti-Human CD40 Recombinant Antibody (Selicrelumab) (TAB-470CQ) in HPLC
HPLC analysis of TAB-470CQ shows the purity is>95%.
Figure 3 Anti-Human CD40 Recombinant Antibody (Selicrelumab) (TAB-470CQ) in WB
Western blot analysis of TAB-470CQ was performed by loading human CD40.
TAB-470CQ incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane1: Reducing antigen (0.1μg)
Lane2: Reducing antigen (0.3μg)
Lane3: Reducing antigen (0.6μg)
Figure 4 Anti-Human CD40 Recombinant Antibody (Selicrelumab) (TAB-470CQ) in ELISA
ELISA analysis of TAB-470CQ was performed by coating with human CD40.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG2, κ
- Specificity
- Human CD40
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- CAS
- 1622140-49-1
- Generic Name
- Selicrelumab
- UNII
- 0O39RGI33V
- Related Disease
- Solid tumors
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The CD40 antibody has been reported in applications of PK.
Pharmacokinetic: Lucatumumab serum levels were collected before dosing, at the end of the infusion, 2 h after the end of the infusion and 24, 48, 96 and 168 h after the start of the first and fourth infusions. Additional time points beyond 168 h were collected after the fourth infusion at 336, 504, 672 and 840 h and every other week thereafter as well as before and after the second and third infusions.
Target
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Selicrelumab"
Afuco™ Anti-CD40 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-470CQ)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD40. It is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.
See other products for "CD40"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1269z | Mouse Anti-CD40 Recombinant Antibody (clone 27G1) | FC, FuncS | Mouse IgG1, κ |
HPAB-0162-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0162-YC) | FC | Human IgG |
HPAB-0163-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0163-YC) | FC | Human IgG |
HPAB-0164-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0164-YC) | FC, Agonist | Human IgG |
HPAB-0165-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0165-YC) | FC | Human IgG |
Customer Reviews and Q&As
Highly Reliable in Cancer Research
Excellent for Flow Cytometry
A Robust Tool for Immunoprecipitation
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-470CQ, RRID: AB_3111960)
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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