Anti-Human CD40 Recombinant Antibody (Selicrelumab)
CAT#: TAB-470CQ
Recombinant monoclonal antibody to CD40. Selicrelumab is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.







Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG2, κ
- Specificity
- Human CD40
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- CAS
- 1622140-49-1
- Generic Name
- Selicrelumab
- UNII
- 0O39RGI33V
- Related Disease
- Solid tumors
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The CD40 antibody has been reported in applications of PK.
Pharmacokinetic: Lucatumumab serum levels were collected before dosing, at the end of the infusion, 2 h after the end of the infusion and 24, 48, 96 and 168 h after the start of the first and fourth infusions. Additional time points beyond 168 h were collected after the fourth infusion at 336, 504, 672 and 840 h and every other week thereafter as well as before and after the second and third infusions.
Target
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Q&As
-
What research applications is Selicrelumab suitable for?
A: Selicrelumab is primarily used in applications such as ELISA, immunohistochemistry (IHC), flow cytometry (FC), and immunoprecipitation (IP). These methods help in analyzing the expression of CD40 in various samples and understanding its implications in solid tumors.
-
What diseases can Selicrelumab help study?
A: This antibody is particularly useful in studying solid tumors. Its ability to target CD40 makes it a valuable tool in cancer research, providing insights into immune response modulation and tumor progression.
-
Is this antibody available in a conjugated form?
A: While the standard offering is unconjugated, there are conjugation options available, such as PE, APC, Biotin, and FITC. These can be selected according to the specific needs of the research being conducted.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-470CQ, RRID: AB_3111960)
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Related Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Selicrelumab"
Afuco™ Anti-CD40 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-470CQ)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD40. It is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.
See other products for "CD40"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G079E | Anti-CD40 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0063CL-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-03) | ELISA, FuncS | |
TAB-0064CL-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-04) | ELISA, FuncS | |
TAB-0065CL-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-05) | ELISA, FuncS | |
TAB-0066CL-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-06) | ELISA, FuncS | |
TAB-0067CL-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (PPAT-071-07) | ELISA, FuncS |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-188LC | Anti-Human CD40 Recombinant Antibody (chi220) | SPR, ELISA, Inhib, FuncS | Chimeric antibody (mouse/human) |
TAB-202LC | Anti-CD40 Recombinant Antibody (TAB-202LC) | ELISA, FC, FuncS | Chimeric (mouse/rhesus) IgG1 |
TAB-203LC | Anti-CD40 Recombinant Antibody (TAB-203LC) | ELISA, FC, FuncS | Chimeric (mouse/rhesus) IgG4 |
TAB-188LC-S(P) | Anti-Human CD40 Recombinant Antibody scFv Fragment (chi220) | SPR, ELISA | Chimeric antibody (mouse/human) |
TAB-192LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-192LC-S(P)) | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-195LC | Human Anti-CD40 Recombinant Antibody (TAB-195LC) | ELISA, Agonist | Human IgG2 |
TAB-196LC | Human Anti-CD40 Recombinant Antibody (TAB-196LC) | ELISA, Agonist | Human IgG2 |
TAB-197LC | Human Anti-CD40 Recombinant Antibody (TAB-197LC) | ELISA, Agonist | Human IgG2 |
TAB-198LC | Human Anti-CD40 Recombinant Antibody (TAB-198LC) | ELISA | Human IgG2 |
TAB-006ML | Anti-Human CD40 Recombinant Antibody (Bleselumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG4, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-189LC-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (F4) | SPR, ELISA | Humanized antibody |
TAB-190LC-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (L3.17) | SPR, ELISA | Humanized antibody |
TAB-194LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-194LC-F(E)) | ELISA | Humanized Fab |
TAB-200LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-200LC-F(E)) | ELISA | Human Fab |
TAB-204LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-204LC-F(E)) | SPR, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-362CQ | Human Anti-CD40 Recombinant Antibody (clone 5D12) | Block, ELISA, FC, SPR, IP, IHC | Human IgG4, κ |
NEUT-363CQ | Mouse Anti-CD40 Recombinant Antibody (clone 5C3) | FC, Block, Activ | Mouse IgG1, κ |
NEUT-366CQ | Rat Anti-CD40 Recombinant Antibody (clone MAB0819) | Block, Activ | Rat IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-364CQ | Mouse Anti-CD40 Recombinant Antibody (clone CBL829) | WB, Neut | Mouse IgG2b, κ |
NEUT-367CQ | Mouse Anti-CD40 Recombinant Antibody (clone CBL013) | WB, IHC, Neut | Mouse IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-365CQ | Hamster Anti-CD40 Recombinant Antibody (clone HM40-3) | FC, Block, Costim, IHC | Hamster IgM |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4059 | Hi-Affi™ Rabbit Anti-CD40 Recombinant Antibody (clone SI126DS) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-105LC | Human Anti-CD40 Recombinant Antibody (MOB-105LC) | FC, FuncS | Human IgG1, κ |
VS-0724-XY18 | Mouse Anti-CD40 Agonistic Antibody (VS-0724-XY18) | FC, Agonistic assays, CyTOF®, ICC | Mouse IgG2b |
VS-0724-XY19 | Rat Anti-Cd40 Agonistic Antibody (VS-0724-XY19) | FC, IP, Agonistic assays, CyTOF® | Rat IgG2a |
VS-0724-XY20 | Rabbit Anti-Cd40 Agonistic Antibody (VS-0724-XY20) | FC, WB, FuncS, Activ, Agonistic assays | Rabbit IgG, kappa |
VS-0724-XY21 | Rat Anti-Cd40 Agonistic Antibody (clone FGK45) | FC, WB, FuncS, Activ, Agonistic assays | Rat IgG2a, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0162-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0162-YC-S(P)) | FC | Human scFv |
HPAB-0163-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0163-YC-S(P)) | FC | Human scFv |
HPAB-0164-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0164-YC-S(P)) | FC, Agonist | Human scFv |
HPAB-0165-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0165-YC-S(P)) | FC | Human scFv |
HPAB-0166-YC-S(P) | Human Anti-CD40 Recombinant Antibody (clone S2C6); scFv Fragment | FC, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-021CN | Human Anti-CD40 Recombinant Antibody (NS-021CN) | ELISA, IF, Block, FuncS | Human IgG |
NS-021CN-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (NS-021CN-F(E)) | ELISA | Human Fab |
NS-021CN-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (NS-021CN-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0009-WJ-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-0009-WJ-F(E)) | ELISA | Human Fab |
HPAB-1662LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1662LY-F(E)) | ELISA, RIA | Mouse Fab |
HPAB-1663LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1663LY-F(E)) | ELISA, RIA | Mouse Fab |
HPAB-1664LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1664LY-F(E)) | ELISA, RIA | Mouse Fab |
HPAB-1665LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1665LY-F(E)) | ELISA, RIA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABC-256 | Mouse Anti-CD40 Recombinant Antibody (PABC-256) | ELISA, FC, WB, Agonist | Mouse IgG |
HPAB-M0481-YC | Human Anti-CD40 Recombinant Antibody (HPAB-M0481-YC) | ELISA, FC | Human IgG |
HPAB-M0482-YC | Human Anti-CD40 Recombinant Antibody (HPAB-M0482-YC) | ELISA, FC | Human IgG |
HPAB-M0483-YC | Human Anti-CD40 Recombinant Antibody (HPAB-M0483-YC) | ELISA, FC | Human IgG |
HPAB-M0484-YC | Human Anti-CD40 Recombinant Antibody (HPAB-M0484-YC) | ELISA, FC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-152 | Afuco™ Anti-CD40 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-152) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-262 | Afuco™ Anti-CD40 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-262) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
AFC-TAB-759 | Afuco™ Anti-CD40 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-759) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
AFC-TAB-470CQ | Afuco™ Anti-CD40 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-470CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
AFC-TAB-006ML | Afuco™ Anti-CD40 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-006ML) | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1218WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (HPAB-1218WJ) | ELISA | Llama VHH |
HPAB-1219WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (HPAB-1219WJ) | ELISA | Llama VHH |
HPAB-1220WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (HPAB-1220WJ) | ELISA | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0724-YC1328 | AbPlus™ Anti-CD40 Magnetic Beads (VS-0724-YC1328) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0924-YC117 | Mouse Anti-CD40 Recombinant Antibody Hexamer (VS-0924-YC117), CDC Enhanced | ELISA, ADCC, CDC | Antibody hexamer |
VS-0924-YC118 | Human Anti-CD40 Recombinant Antibody Hexamer (VS-0924-YC118), CDC Enhanced | ELISA, Block, FC, IF, Activ, CDC | Antibody hexamer |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0225-XY52 | CytoStream™ Armenian Hamster Anti-CD40 Recombinant Antibody (clone HM40-3) | FC, Block | Armenian Hamster IgM, kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-FY89 | Rat Anti-CD40 (clone FGK45) scFv-Fc Chimera | FC, WB, Agonist | Rat IgG1, scFv-Fc |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0425-YC514 | Recombinant Anti-CD40 Vesicular Antibody, EV Displayed (VS-0425-YC514) | ELISA, FC, Neut, Cell-uptake |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY1181 | Anti-CD40 Immunohistochemistry Kit | IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-YC30 | Recombinant Anti-CD40 (CRD1 x ECD) Biparatopic Antibody, Tandem scFv | ELISA, FC, Neut, IHC, IP, IF | Tandem scFv |
VS-0525-YC206 | Recombinant Anti-CD40 (CRD2 x CRD1) Biparatopic Antibody, Tandem scFv | ELISA, FC, IF, IHC, IP | Tandem scFv |
VS-0525-YC208 | Recombinant Anti-CD40 Biparatopic Antibody, Tandem scFv (Bleselumab x Selicrelumab) | ELISA, FC, IP, IF, IHC | Tandem scFv |
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