EETI-II anti-CELA1 (SEE-L086)
The EETI-II that bound Porcine pancreatic elastase (PPE) was isolated from the library using mRNA display techonology. After affinity maturation, EETI-II variants were identified having affinities (KD=24 pM) for Porcine pancreatic elastase (PPE) as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specifications
- Scaffold Name
- EETI-II
- Origin
- Trypsin-specific squash inhibitor EETI II
- Core Structure
- Coiled, cys-rich (28)
- Variable Regions
- 6 aa
- Target
- Porcine pancreatic elastase (PPE)
- Species Reactivity
- Porcine
- Expression Host
- E. coli
- Affinity Constant
- 24 pM
- Applications
- ELISA; IHC; Microscopy; FC; WB; FuncS
Target
- Alternative Names
- trypsin-specific squash inhibitor EETI II; EETI-II; ELA1; ELS1; Elastase-1
- Entrez Gene ID
- 396766
- UniProt ID
- P00772
For lab research use only, not for diagnostic, therapeutic or any in vivo human use.
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