PDZ domain scaffold protein anti-Human hPMCA4b

CAT#: SPD-L151

The PDZ domain that bound hPMCA4b was isolated from the library using Phage display techonology. PDZ domains are modular protein-interaction domains that are specialized for binding to short peptide motifs at the extreme carboxy (C) termini of other proteins, athough they can also have other modes of interaction. After affinity maturation, PDZ domain variants were identified having affinities for hPMCA4b as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.

Gene Expression
Figure 1 IF staining of human cell line A-431 Figure 2 Endometrium 1 Figure 3 Testis Figure 4 Endometrium Figure 5 Lymph node Figure 6 Cerebral cortex Figure 7 Colon Figure 8 Liver Figure 9 Kidney Figure 10 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, SuSa)

Specifications

  • Scaffold Name
  • PDZ domain
  • Origin
  • hDlg
  • Target
  • hPMCA4b
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • ELISA; IHC; Microscopy; FC; WB; FuncS

Target

  • Alternative Names
  • hDlg; PDZ domain; MXRA1; PMCA4; ATP2B2; PMCA4b; PMCA4x
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