PE-B*27:05/Human EIF3D (SQFGGGSQY) MHC Tetramer (CAT#: MHC-LC4375)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human EIF3D of peptide SQFGGGSQY covering 61-69 and B*27:05 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

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Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • B*27:05
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • EIF3D
  • Antigen Species
  • Human
  • Peptide
  • SQFGGGSQY
  • Range
  • 61-69
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • EIF3D; Eukaryotic translation initiation factor 3 subunit D; EIF3S7; eIF3-p66; eIF3-zeta

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