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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    PE-Mamu-B*001:01/Human AP2B1 (LDSLRDLI) MHC Tetramer (CAT#: MHC-LC4331)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human AP2B1 of peptide LDSLRDLI covering 105-112 and Mamu-B*001:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
    Size *:
    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/56733/if_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17631/if_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human appendix
    Figure 3 IHC staining of human appendix
    (Immunohistochemical staining of human appendix shows strong cytoplasmic positivity in granular.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/17631/40052_A_3_2_selected.jpg
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/67983/161970_B_9_5.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/67983/161970_A_9_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/67983/161970_A_9_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/67983/161970_A_5_6.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000006125-AP2B1

    Specifications

    • Allele
    • Mamu-B*001:01
    • Class
    • Class I
    • MHC Species
    • Macaca
    • Antigen
    • AP2B1
    • Antigen Species
    • Human
    • Peptide
    • LDSLRDLI
    • Range
    • 105-112
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    • Alternative Names
    • AP2B1; Beta adaptin subunit; ADTB2; AP105B; CLAPB1; AP2-BETA

    Downloads

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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