A*02:01/Human PASD1 (RLWQELSDI) MHC Pentamer (CAT#: MHC-YF364)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Circadian clock protein PASD1-derived peptide of RLWQELSDI sequence covering 691-700 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/1216_A2_5_selected.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/1216_A2_5_selected.jpg
Figure 2 High expression in testis
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/26915_A_4_6_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/26915_A_4_6_val_selected.jpg
Figure 3 Low expression in endometrium 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/26915_B_4_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/26915_B_4_3_val_selected.jpg
Figure 4 Colon
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/26915_A_9_3.jpg
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/26915_A_9_3.jpg
Figure 5 Testis
(Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/26915_A_4_6.jpg
(Preleptotene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11122/26915_A_4_6.jpg
Figure 6 RNA cell line category: Group enriched (BEWO, HMC-1, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166049-PASD1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166049-PASD1
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- PASD1
- Antigen Species
- Human
- Peptide
- RLWQELSDI
- Range
- 691-700
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]
- Alternative Names
- PAS Domain Containing Repressor 1; Cancer/Testis Antigen 63; PAS Domain Containing 1; CT63; PAS Domain-Containing Protein 1; Circadian Clock Protein PASD1; OX-TES-1; OXTES1; CT64;
- Gene ID
- 139135
- UniProt ID
- Q8IV76
Downloads
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MHC Tetramer Products for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1125 | PE-A*02:01/Human PASD1 (QLLDGFMITL) MHC Tetramer | FCM, IHC | |
| MHC-CN1126 | APC-A*02:01/Human PASD1 (QLLDGFMITL) MHC Tetramer | FCM, IHC | |
| MHC-YF656 | A*02:01/Human PASD1 (YLVGNVCIL) MHC Pentamer | FCM | |
| MHC-YF657 | A*02:01/Human PASD1 (QLLDGFMITL) MHC Pentamer | FCM | |
| MHC-YF658 | A*02:01/Human PASD1 (ELSDSLGPV) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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