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A*02:01/Human Heparanase (DLIFGLNAL) MHC Pentamer (CAT#: MHC-YF473)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Heparanase-derived peptide of DLIFGLNAL sequence covering 185-193 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55344/874_A7_1_red_green.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & Vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55344/886_H3_2_red_green.jpg
Figure 3 IF staining of human cell line HeLa
Figure 3 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55344/881_A7_1_red_green.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707, OE19, TIME)
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707, OE19, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000173083-HPSE

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • Heparanase
  • Antigen Species
  • Human
  • Peptide
  • DLIFGLNAL
  • Range
  • 185-193
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • Alternative Names
  • Heparanase; Endo-Glucoronidase; Heparanase-1; HPSE1; HPA1; HPR1;

Downloads

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Single-domain Antibody

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NAB-673-sdAb Recombinant Anti-human HPSE VHH Single Domain Antibody FUNC, FA, IP, ChiP Llama VHH

Human Antibody

CAT Product Name Application Type
TAB-025CT Anti-Human Heparanase Recombinant Antibody (10E9.1) ELISA, Inhibition, FC Human antibody
TAB-025CT-S(P) Anti-Human Heparanase Recombinant Antibody scFv Fragment (10E9.1) ELISA, Inhibition, FC Human antibody
TAB-025CT-F(E) Anti-Human Heparanase Recombinant Antibody Fab Fragment (10E9.1) ELISA, Inhibition, FC Human antibody
TAB-280CQ Anti-Human HPSE Recombinant Antibody (22D9) FuncS, Inhib Human antibody
TAB-280CQ-S(P) Anti-Human HPSE Recombinant Antibody scFv Fragment (22D9) ELISA, FC, WB Human antibody

Recombinant Antibody

CAT Product Name Application Type
MOB-0628CT Recombinant Mouse anti-Human HPSE Monoclonal antibody (EML1141) WB
HPAB-0264-YC Mouse Anti-HPSE Recombinant Antibody (HPAB-0264-YC) WB, IF Mouse IgM
HPAB-0265-YC Mouse Anti-HPSE Recombinant Antibody (HPAB-0265-YC) FC, Neut, FuncS Mouse IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1672 Rabbit Anti-HPSE Recombinant Antibody (clone DS1672AB) WB, IP Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0264-YC-S(P) Mouse Anti-HPSE Recombinant Antibody; scFv Fragment (HPAB-0264-YC-S(P)) FC, Neut, FuncS Mouse scFv
HPAB-0265-YC-S(P) Mouse Anti-HPSE Recombinant Antibody; scFv Fragment (HPAB-0265-YC-S(P)) FC, Neut, FuncS Mouse scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0264-YC-F(E) Mouse Anti-HPSE Recombinant Antibody; Fab Fragment (HPAB-0264-YC-F(E)) FC, Neut, FuncS Mouse Fab
HPAB-0265-YC-F(E) Mouse Anti-HPSE Recombinant Antibody; Fab Fragment (HPAB-0265-YC-F(E)) FC, Neut, FuncS Mouse Fab

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-CN0853 PE-A*02:01/Human HPSE (LLLGPLGPL) MHC Tetramer FCM, IHC
MHC-CN0854 APC-A*02:01/Human HPSE (LLLGPLGPL) MHC Tetramer FCM, IHC
MHC-CN0855 FITC-A*02:01/Human HPSE (LLLGPLGPL) MHC Tetramer FCM, IHC
MHC-CN0856 A*02:01/Human HPSE (LLLGPLGPL) MHC Tetramer FCM, IHC
MHC-YF472 A*02:01/Human Heparanase (ALPPPLMLL) MHC Pentamer FCM

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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