A*02:01/HIV Pol (VIYHYVDDL) MHC Pentamer (CAT#: MHC-YF668)

• Allele
• A*02:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• Pol

• Antigen Species
• HIV

• Peptide
• VIYHYVDDL

• Conjugate
• Unlabeled, Biotin, R-PE, APC

• Application
• FCM

• Antigen Introduction
• Gag-Pol polyprotein: Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi). Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. At low concentration, the polyprotein would promote translation, whereas at high concentration, the polyprotein would encapsidate genomic RNA and then shut off translation.

• Alternative Names
• Gag-Pol polyprotein; Pr160Gag-Pol; gag-pol

• Gene ID
• 155348

• UniProt ID
• P04585

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