A*68:01/Human NY-ESO-1 (TVSGNILTIR) MHC Pentamer (CAT#: MHC-YF644)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed NY-ESO-1-derived peptide of TVSGNILTIR sequence covering 127-136 and A*68:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Testis
(Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15453/34589_A_6_6.jpg
(Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/15453/34589_A_6_6.jpg
Figure 2 RNA cell line category: Cell line enriched (U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184033-CTAG1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184033-CTAG1B
Figure 2 RNA cell line category: Cell line enriched (U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184033-CTAG1B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184033-CTAG1B
Specifications
- Allele
- A*68:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- NY-ESO-1
- Antigen Species
- Human
- Peptide
- TVSGNILTIR
- Range
- 127-136
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence.
- Alternative Names
- Cancer/Testis Antigen 1B; Autoimmunogenic Cancer/Testis Antigen NY-ESO-1; Cancer/Testis Antigen 6.1; L Antigen Family Member 2; Cancer/Testis Antigen 1; LAGE-2; LAGE2B; CT6.1; CTAG1;
- Gene ID
- 1485
- UniProt ID
- P78358
Downloads
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