Mouse Anti-CAPN6 Recombinant Antibody (VS3-FY2644) (CAT#: VS3-FY2644)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Calpain 6 of human and mouse origins

• Species Reactivity
• Human, Mouse

• Applications
• WB

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 74.6 kDa.

• Related Disease
• Leiomyosarcoma and Leiomyoma

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000

• Alternative Names
• Calpain 6; Calpain-Like Protease X-Linked; Calpamodulin; CANPX; CalpM; DJ914P14.1; Calpain-6; EC 3.4.22; CAPNX

• Gene ID
• 827

• UniProt ID
• Q9Y6Q1

• Sequence Similarities
• Belongs to the peptidase C2 family.

• Cellular Localization
• Cytoplasm, perinuclear region
  Cytoplasm, cytoskeleton, spindle

• Post Translation Modifications
• Modification sites at PhosphoSitePlus
  Modification sites at neXtProt

• Protein Refseq
• NP_055104.2

• Function
• May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility.
  Does not seem to have protease activity as it has lost the active site residues (By similarity).

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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