Human Anti-CD33 Recombinant Antibody (clone huM195) (CAT#: FAMAB-0045CQ)
Recombinant Human Antibody clone huM195, which is specific to CD33. The humanized M195 antibody, which has reshaped V regions, have higher apparent binding affinity for the CD33 Ag than the chimeric or mouse antibodies.
Specific Inquiry
FuncS
Figure 1 Overall survival analysis: HuM195 (lintuzumab) -treated versus control patients
Feldman, E. J., Brandwein, J., Stone, R., Kalaycio, M., Moore, J., O'Connor, J., ... & Jurcic, J. C. (2005). Phase III randomized multicenter study of a humanized anti-CD33 monoclonal antibody, lintuzumab, in combination with chemotherapy, versus chemotherapy alone in patients with refractory or first-relapsed acute myeloid leukemia. Journal of Clinical Oncology, 23(18), 4110-4116.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG1
- Specificity
- Human CD33
- Species Reactivity
- Human
- Clone
- huM195
- Applications
- ELISA, FC, FuncS
- Related Disease
- AML
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Functional Assay.
Target
- Alternative Names
- CD33 Molecule; Sialic Acid Binding Ig-Like Lectin 3; Sialic Acid-Binding Ig-Like Lectin 3; CD33 Antigen (Gp67); SIGLEC-3; SIGLEC3; Gp67; CD33 Antigen; P67
- Gene ID
- 945
- UniProt ID
- P20138
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-321-sdAb | Recombinant Anti-human CD33 VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
Customer Reviews and Q&As
Customer Review
Q&As
-
High satisfaction
My satisfaction with the Human Anti-CD33 Recombinant Antibody (clone huM195) is very high. -
Effective and manageable
The Human Anti-CD33 Recombinant Antibody (clone huM195) has been both effective and manageable in treating AML. -
Superior option
The Human Anti-CD33 Recombinant Antibody (clone huM195) has proven to be a superior treatment option for AML. It effectively targets cancer cells, reducing the side effects at the same time.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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