Human Anti-CD33 Recombinant Antibody (clone huM195)
CAT#: FAMAB-0045CQ
Recombinant Human Antibody clone huM195, which is specific to CD33. The humanized M195 antibody, which has reshaped V regions, have higher apparent binding affinity for the CD33 Ag than the chimeric or mouse antibodies.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64807/1186_A4_3_selected.jpg
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Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG1
- Specificity
- Human CD33
- Species Reactivity
- Human
- Clone
- huM195
- Applications
- ELISA, FC, FuncS
- Related Disease
- AML
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Functional Assay.
Target
REVIEWS AND Q&AS
CITATIONS
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Customer Review
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High satisfaction
My satisfaction with the Human Anti-CD33 Recombinant Antibody (clone huM195) is very high.
Effective and manageable
The Human Anti-CD33 Recombinant Antibody (clone huM195) has been both effective and manageable in treating AML.
Superior option
The Human Anti-CD33 Recombinant Antibody (clone huM195) has proven to be a superior treatment option for AML. It effectively targets cancer cells, reducing the side effects at the same time.
Q&As
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What is the intended application of the clone huM195 Human Anti-CD33 Recombinant Antibody?
A: The Human Anti-CD33 Recombinant Antibody (clone huM195) is primarily used to target and treat acute myeloid leukemia (AML) by binding specifically to the CD33 antigen expressed on leukemic cells, facilitating their destruction while sparing healthy cells that do not have this antigen.
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When compared to conventional therapies, what are the advantages of utilizing the Human Anti-CD33 Recombinant Antibody (clone huM195)?
A: Benefits include targeted action against leukemic cells, reduced side effects, improved quality of life due to less systemic toxicity, and potentially higher remission rates. This antibody's specificity helps to spare healthy cells, thus minimizing the adverse effects commonly associated with chemotherapy.
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What are the Human Anti-CD33 Recombinant Antibody's (clone huM195) long-term advantages?
A: Long-term benefits include prolonged remission periods, potentially improved survival rates, and better quality of life due to fewer side effects and reduced systemic toxicity.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone HuM195"
- CAT
- Product Name
See other products for "CD33"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-321-sdAb | Recombinant Anti-human CD33 VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-013 | Humanized Anti-CD33 Recombinant Antibody (TAB-013) | IF, IP, Neut, FuncS, ELISA, FC, WB | Humanized (from mouse) IgG4, κ |
| TAB-H37 | Anti-Human CD33 Recombinant Antibody (Gemtuzumab Ozogamicin) | ELISA, FC, IP, FuncS, IF, Neut, IHC | IgG |
| TAB-756 | Anti-CD33 Recombinant Antibody (TAB-756) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
| VS3-WK1523 | Human Anti-CD33 Recombinant Antibody (clone CDP-771) | FC | Humanized IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G008E | Anti-CD33 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G008G | Anti-CD33 immunotoxin (scFv)-Gel | Cytotoxicity assay, Function study | |
| AGTO-L050E | anti-CD33 immunotoxin M195 (IgG)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L050G | anti-CD33 immunotoxin M195 (IgG)-Gel | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-119LC | Mouse Anti-CD33 Recombinant Antibody (TAB-119LC) | ELISA, IF, RIA | Mouse IgG |
| TAB-120LC | Mouse Anti-CD33 Recombinant Antibody (TAB-120LC) | ELISA, Cyt | Mouse IgG |
| TAB-121LC | Mouse Anti-CD33 Recombinant Antibody (TAB-121LC) | ELISA | Mouse IgG |
| TAB-122LC | Mouse Anti-CD33 Recombinant Antibody (TAB-122LC) | ELISA, Cyt | Mouse IgG |
| TAB-124LC | Mouse Anti-CD33 Recombinant Antibody (TAB-124LC) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-123LC | Anti-Human CD33 Recombinant Antibody | FC | Human antibody |
| TAB-146LC | Human Anti-CD33 Recombinant Antibody (TAB-146LC) | ELISA | Human IgG |
| TAB-123LC-S(P) | Anti-Human CD33 Recombinant Antibody scFv Fragment | FC | Human antibody |
| TAB-123LC-F(E) | Anti-Human CD33 Recombinant Antibody Fab Fragment | FC | Human antibody |
| TAB-146LC-F(E) | Human Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-146LC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-013LC | Recombinant Anti-Human CD33 Antibody (Fab glycosylation) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC162 | APC-A*02:01/Human CD33 (AIISGDSPV) MHC Tetramer | FCM | |
| MHC-LC163 | PE-A*02:01/Human CD33 A65Y (YIISGDSPV) MHC Tetramer | FCM | |
| MHC-LC164 | APC-A*02:01/Human CD33 A65Y (YIISGDSPV) MHC Tetramer | FCM | |
| MHC-CN0509 | PE-A*02:01/Human CD33 (YLISGDSPV) MHC Tetramer | FCM, IHC | |
| MHC-CN0510 | APC-A*02:01/Human CD33 (YLISGDSPV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-341CQ | Mouse Anti-CD33 Recombinant Antibody (clone WM53) | FC, IHC-Fr, ICC, IP, WB, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0553 | Hi-Affi™ Rabbit Anti-CD33 Recombinant Antibody (clone DS553AB) | WB, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-471CQ | Anti-Human CD33 Recombinant Antibody (TAB-471CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0077-LSX-S(P) | Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0077-LSX-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0078-LSX-S(P) | Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0078-LSX-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0079-LSX-S(P) | Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0079-LSX-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0080-LSX-S(P) | Human Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0080-LSX-S(P)) | ELISA | Human scFv |
| HPAB-0081-LSX-S(P) | Human Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0081-LSX-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0077-LSX-F(E) | Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-0077-LSX-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0078-LSX-F(E) | Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-0078-LSX-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0079-LSX-F(E) | Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-0079-LSX-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0080-LSX-F(E) | Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-0080-LSX-F(E)) | ELISA | Human Fab |
| HPAB-0081-LSX-F(E) | Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-0081-LSX-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-471CQ | Afuco™ Anti-CD33 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-471CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-756 | Afuco™ Anti-CD33 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-756) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-013 | Afuco™ Anti-CD33 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-013) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1910LY | Human Anti-CD33 Recombinant Antibody (HPAB-1910LY) | FC, Inhib, FuncS | Humanized IgG |
| HPAB-1911LY | Human Anti-CD33 Recombinant Antibody (HPAB-1911LY) | FC, SPR, FuncS | Humanized IgG |
| HPAB-1912LY | Human Anti-CD33 Recombinant Antibody (HPAB-1912LY) | FC | Humanized IgG |
| HPAB-1913LY | Human Anti-CD33 Recombinant Antibody (HPAB-1913LY) | FC, SPR | Humanized IgG |
| HPAB-1914LY | Human Anti-CD33 Recombinant Antibody (HPAB-1914LY) | FC | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC24 | Rabbit Anti-CD33 Antibody (VS-0924-YC24) - Cancer Stem Cell Marker | IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY35 | CytoStream™ Mouse Anti-CD33 Recombinant Antibody (clone HIM3-4) | FC | Mouse IgG1, kappa |
| VS-0225-XY36 | CytoStream™ Mouse Anti-CD33 Recombinant Antibody (clone P67.6) | FC | Mouse IgG1, kappa |
| VS-0225-XY37 | CytoStream™ Mouse Anti-CD33 Recombinant Antibody (clone WM53) | FC | Mouse IgG1, kappa |
| VS13-YC160 | CytoStream™ Mouse Anti-CD33 Recombinant Antibody (VS13-YC160) | IHC-P, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY84 | Mouse Anti-CD33 scFv-Fc Chimera (VS-0425-FY84) | FC, IF | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC365 | Recombinant Anti-CD33 Vesicular Antibody, EV Displayed (VS-0425-YC365) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1159 | Anti-CD33 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1160 | Anti-Human CD33 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC28 | Recombinant Anti-CD33 (IgV domain x IgC domain) Biparatopic Antibody, Tandem scFv | ELISA | Tandem scFv |
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