Rabbit Anti-CTSZ Recombinant Antibody (clone R09-9J9)
CAT#: VS3-FY1674
This antibody is applicable in IHC. It is a rabbit recombinant monoclonal antibody that is specifically created to bind human CTSZ. It is also known as CTSX, Cathepsin Z. It exhibits carboxyl monopeptidase and carboxyl dipeptidase activities. The R09-9J9 is recommended for dilution of target protein by western blot (dilution 1/500-1/1000), immunohistochemistry (dilution 1/50-1/100).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49876/807_H6_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25114/54716_A_8_2_selected.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25114/54716_A_8_8.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25114/54716_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25114/54716_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25114/54716_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25114/54716_A_4_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (fHDF/TERT166)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101160-CTSZ
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Specifications
- Immunogen
- Recombinant human cathepsin Z protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CTSZ
- Species Reactivity
- Human
- Clone
- R09-9J9
- Applications
- Western Blot, Immunohistochemistry-Paraffin
- MW
- The calculated weight of the target protein is approximately 34 kDa, while the observed molecular weight stands at 34 kDa.
- Related Disease
- Dacryoadenitis
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- Cathepsin Z; Cathepsin X; Cysteine-Type Carboxypeptidase; Lysosomal Carboxypeptidase B; Carboxypeptidase LB; Cathepsin IV; Cathepsin B2
- Gene ID
- 1522
- UniProt ID
- Q9UBR2
- Sequence Similarities
- Belongs to the peptidase C1 family.
- Cellular Localization
- Lysosome
- Post Translation Modifications
- Disulfide bond
Glycoprotein
Zymogen
- Protein Refseq
- NP_001327.2
- Function
- Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Capable of producing kinin potentiating peptides (By similarity).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CTSZ"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0331CT | Recombinant Mouse anti-Human CTSZ Monoclonal antibody (NN0245-8M27) | WB | |
| MOB-253YJL | Rabbit Anti-CTSZ Recombinant Antibody (clone CBC238) | ELISA, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0871 | Hi-Affi™ Rabbit Anti-CTSZ Recombinant Antibody (clone DS871AB) | ELISA | Rabbit IgG |
| MOR-4121 | Hi-Affi™ Rabbit Anti-CTSZ Recombinant Antibody (clone SI192DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY582 | Anti-CTSZ Immunohistochemistry Kit | IHC |
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