AbPlus™ Anti-GLA Magnetic Beads (VS-0724-YC337) (CAT#: VS-0724-YC337)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-GLA specific antibody

• Target
• GLA

• Immunogen
• Recombinant human alpha-Galactosidase A/GLA, aa 1-429.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq, Jul 2008]

• Alternative Names
• Galactosidase Alpha; Alpha-D-Galactosidase A; EC 3.2.1.22; Melibiase; Alpha-D-Galactoside Galactohydrolase 1; Alpha-D-Galactoside Galactohydrolase; Alpha-Galactosidase A;

• Gene ID
• 2717

• UniProt ID
• P06280

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