Human Anti-HIV-1 gp120 V2 Recombinant Antibody (clone RE505-22) (CAT#: PABC-480)

This product is a recombinant Human antibody that can recognize HIV-1 gp120 V2.


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ELISA

Figure 1 Chimeric humanized mouse Abs bind a gp120 V2 linear epitope.

Figure 1 Chimeric humanized mouse Abs bind a gp120 V2 linear epitope.

Only the four chimeric humanized mouse Abs (red lines) bound V2 peptide. Binding was measured by ELISA, and values are reported as OD at 450 nm or the natural LogAUC.

Wiehe, K., Nicely, N. I., Lockwood, B., Kuraoka, M., Anasti, K., Arora, S., ... & Xia, S. M. (2017). Immunodominance of antibody recognition of the HIV envelope V2 region in Ig-humanized mice. The Journal of Immunology, 198(3), 1047-1055.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, κ
  • Specificity
  • HIV-1 gp120 V2
  • Species Reactivity
  • HIV-1
  • Clone
  • RE505-22
  • Applications
  • ELISA, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Enzyme-linked Immunosorbent Assay and Neutralization. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160; precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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