Recombinant Mouse Anti-HopQ Antibody (147.2) (CAT#: FAMAB-0168YC)
HopD and HopQ are members of the predicted family of outer membrane proteins of H. pylori. HopD is a porin with a small pore. The type I hopQ allele has been associated with cagA-positive s1 vacA-type strains from patients with ulcer disease. Its presence in the H. pylori genome is clustered with the Cag pathogenicity island and might contribute to its virulence.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
WB
Figure 1 H. pylori antigen recognition by ScFv clone 147.2.
Western blot of H. pylori cells (lane 1), H. pylori membranes (lane 2), and H. pylori cytoplasm (lane 3) using ScFv 147.2 and chemoluminescence detection.
Sabarth, N., Hurvitz, R., Schmidt, M., Zimny-Arndt, U., Jungblut, P. R., Meyer, T. F., & Bumann, D. (2005). Identification of Helicobacter pylori surface proteins by selective proteinase K digestion and antibody phage display. Journal of microbiological methods, 62(3), 345–349.
FC
Figure 2 H. pylori antigen recognition by ScFv clone 147.2.
ScFv were detected by mouseanti-c-myc IgG, followed by FITC conjugated rat-anti-mouse IgG. Stained H. pylori cells were analysed by FACS.
Sabarth, N., Hurvitz, R., Schmidt, M., Zimny-Arndt, U., Jungblut, P. R., Meyer, T. F., & Bumann, D. (2005). Identification of Helicobacter pylori surface proteins by selective proteinase K digestion and antibody phage display. Journal of microbiological methods, 62(3), 345–349.
Specifications
- Immunogen
- H. pylori lysate
- Host Species
- Mouse
- Derivation
- Phage display library
- Type
- Mouse IgG
- Specificity
- H. pylori HopQ
- Species Reactivity
- H. pylori
- Clone
- 147.2
- Applications
- ELISA, Western Blot
- Related Disease
- Ulcer disease
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- HopQ; Hypothetical outer membrane protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0168-YC-S(P) | Recombinant Mouse Anti-HopQ Antibody scFv Fragment (147.2) | ELISA, WB | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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