Recombinant Mouse Anti-HPV59 L1 Antibody (28F10) (CAT#: PABC-518)
This product is a recombinant Mouse antibody that can recognize HPV59 L1. 28F10 specifically binds to and neutralizes HPV59. 28F10 recognizes the HPV59 FG loop of a single monomer.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Neutralization assay of MAb 28F10 to WT and mutant PsVs of HPV18.
Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.
Figure 2 ELISA was used for evaluation of binding of chimeric VLPs of HPV18 against MAb 28F10.
Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.
Figure 3 Binding profiles of MAb 28F10 to the mutant and WT HPV59 VLP.
Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.
Specifications
- Immunogen
- HPV58 and HPV59 VLPs
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- HPV59 L1
- Species Reactivity
- HPV59
- Clone
- 28F10
- Applications
- ELISA, Neut, WB
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western Blot, Neutralization and Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- HPV59 L1; Human papillomavirus type 59 Major capsid protein L1
- UniProt ID
- Q81971
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
PFBC-518 | Recombinant Mouse Anti-HPV59 L1 Antibody Fab Fragment (28F10) | ELISA, Neut, WB | Mouse Fab |
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