Recombinant Mouse Anti-HPV59 L1 Antibody (28F10) (CAT#: PABC-518)

This product is a recombinant Mouse antibody that can recognize HPV59 L1. 28F10 specifically binds to and neutralizes HPV59. 28F10 recognizes the HPV59 FG loop of a single monomer.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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  • Published Data
  • Datasheet
  • MSDS
  • COA
Neut

Figure 1 Neutralization assay of MAb 28F10 to WT and mutant PsVs of HPV18.

Figure 1 Neutralization assay of MAb 28F10 to WT and mutant PsVs of HPV18.

Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.

ELISA

Figure 2 ELISA was used for evaluation of binding of chimeric VLPs of HPV18 against MAb 28F10.

Figure 2 ELISA was used for evaluation of binding of chimeric VLPs of HPV18 against MAb 28F10.

Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.

Figure 3 Binding profiles of MAb 28F10 to the mutant and WT HPV59 VLP.

Figure 3 Binding profiles of MAb 28F10 to the mutant and WT HPV59 VLP.

Li, Z., Wang, D., Gu, Y., Song, S., He, M., Shi, J., ... & Zheng, Q. (2017). Crystal structures of two immune complexes identify determinants for viral infectivity and type-specific neutralization of human papillomavirus. MBio, 8(5), e00787-17.


Specifications

  • Immunogen
  • HPV58 and HPV59 VLPs
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2a
  • Specificity
  • HPV59 L1
  • Species Reactivity
  • HPV59
  • Clone
  • 28F10
  • Applications
  • ELISA, Neut, WB

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Western Blot, Neutralization and Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • HPV59 L1; Human papillomavirus type 59 Major capsid protein L1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Fab Antibody Products ScFv Antibody Products
CAT Product Name Application Type
PFBC-518 Recombinant Mouse Anti-HPV59 L1 Antibody Fab Fragment (28F10) ELISA, Neut, WB Mouse Fab

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