AbPlus™ Anti-IL12RB1 Magnetic Beads (VS-0724-YC1416)
CAT#: VS-0724-YC1416
The AbPlus Anti-IL12RB1 Magnetic Beads (VS-0724-YC1416) is an innovative affinity resin which is bound with anti-IL12RB1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of IL12RB1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/74414/1688_B12_33_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000096996-IL12RB1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-IL12RB1 specific antibody
- Target
- IL12RB1
- Immunogen
- Synthetic peptide corresponding to the C-terminus of the human IL12RB1/CD212.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
- Alternative Names
- Interleukin 12 Receptor Subunit Beta 1
- Gene ID
- 3594
- UniProt ID
- P42701
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2136z | Mouse Anti-IL12RB1 Recombinant Antibody (clone 3A2) | ELISA, WB | Mouse IgG1 |
| HPAB-0084-FY | Human Anti-IL12RB1 Recombinant Antibody (clone mAb4) | ELISA | Human IgG1 |
| HPAB-0852-CN | Human Anti-IL12RB1 Recombinant Antibody (HPAB-0852-CN) | ELISA, FC | Human IgG4 |
| HPAB-0853-CN | Human Anti-IL12RB1 Recombinant Antibody (HPAB-0853-CN) | ELISA, FC | Human IgG4 |
| HPAB-0854-CN | Human Anti-IL12RB1 Recombinant Antibody (HPAB-0854-CN) | ELISA, FC | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0084-FY-S(P) | Human Anti-IL12RB1 Recombinant Antibody (clone mAb4); scFv Fragment | ELISA | Human scFv |
| HPAB-0852-CN-S(P) | Human Anti-IL12RB1 Recombinant Antibody; scFv Fragment (HPAB-0852-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0853-CN-S(P) | Human Anti-IL12RB1 Recombinant Antibody; scFv Fragment (HPAB-0853-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0854-CN-S(P) | Human Anti-IL12RB1 Recombinant Antibody; scFv Fragment (HPAB-0854-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-674-FY-S(P) | Mouse Anti-IL12RB1 Recombinant Antibody (clone mAb1); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0084-FY-F(E) | Human Anti-IL12RB1 Recombinant Antibody (clone mAb4); Fab Fragment | ELISA | Human Fab |
| HPAB-0852-CN-F(E) | Human Anti-IL12RB1 Recombinant Antibody; Fab Fragment (HPAB-0852-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0853-CN-F(E) | Human Anti-IL12RB1 Recombinant Antibody; Fab Fragment (HPAB-0853-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0854-CN-F(E) | Human Anti-IL12RB1 Recombinant Antibody; Fab Fragment (HPAB-0854-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0848-FY-S(P) | Human Anti-IL12RB1 Recombinant Antibody (clone mAb10); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY127 | CytoStream™ Mouse Anti-IL12RB1 Recombinant Antibody (VS-0225-XY127) | FC | Mouse IgG2a, kappa |
| VS-0225-XY128 | CytoStream™ Mouse Anti-IL12RB1 Recombinant Antibody (VS-0225-XY128) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC541 | Recombinant Anti-IL12RB1 Vesicular Antibody, EV Displayed (VS-0425-YC541) | ELISA, FC, Cell-uptake |
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