Mouse Anti-LIFR Recombinant Antibody (VS3-FY2604) (CAT#: VS3-FY2604)
This recombinant mouse monoclonal antibody has been intricately crafted to target the LIF receptor subunit alpha protein (CD118), a calculated weight of 123.7 kDa. It cross-reacts with human. This monoclonal antibody is potential for conducting research on Stuve-Wiedemann Syndrome 1 and Stüve-Wiedemann Syndrome. This monoclonal antibody can be used in Flow cytometry, ELISA.
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- LIF receptor subunit alpha of human
- Species Reactivity
- Human
- Applications
- FC, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 123.7 kDa.
- Related Disease
- Stuve-Wiedemann Syndrome 1 and Stüve-Wiedemann Syndrome
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- SWS; SJS2; STWS; CD118; LIF-R
- Gene ID
- 3977
- Sequence Similarities
- Belongs to the type I cytokine receptor family. Type 2 subfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn64, Asn85, Asn131, Asn143, Asn191, Asn243, Asn303, Asn390, Asn407, Asn426, Asn445, Asn481, Asn489, Asn572, Asn652, Asn663, Asn680, Asn729, and Asn787
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 22 sites, 2 O-linked glycans (3 sites)
- Protein Refseq
- XP_011512344.1; XP_016864952.1; XP_047273128.1; XP_054208551.1; XP_054208552.1
- Function
- Signal-transducing molecule.
May have a common pathway with IL6ST.
The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-HM348 | Mouse Anti-CD118 Recombinant Antibody (clone 5D3G12) | FCM | Mouse IgG1 |
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