CytoStream™ Mouse Anti-MUC5B Recombinant Antibody (VS13-YC750) (CAT#: VS13-YC750)
The CytoStream™ Mouse Anti-MUC5B Recombinant Antibody is specific for human MUC5B. MUC5B, a mucin family member, forms gel-like mucus, influencing properties like viscosity in fluids. It's upregulated in diseases like COPD and involved in pathogenesis. The anti-MUC5B antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8246/1318_C3_8_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8246/1318_C3_8_selected.jpg
Figure 2 Cervix
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8246/24311_B_9_3_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8246/24311_B_9_3_val_selected.jpg
Figure 3 Nasopharynx
(Respiratory epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8246/24311_B_9_2.jpg
(Respiratory epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8246/24311_B_9_2.jpg
Figure 4 Colon
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8246/24400_A_7_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8246/24400_A_7_3.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9396/34513_A_6_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9396/34513_A_6_6.jpg
Figure 6 RNA cell line category: Group enriched (OE19, PC-3)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117983-MUC5B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117983-MUC5B
Specifications
- Immunogen
- Recombinant human MUC5B expressed in E. coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human MUC5B
- Species Reactivity
- Human
- Applications
- IHC-P, FC, ELISA
- Conjugate
- NONE
- Related Disease
- Sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, Chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease
Product Property
- Clonality
- Monoclonal
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Flow cytometry (FC): 1/50-1/100
ELISA: 1/10000
Target
- Alternative Names
- Mucin 5B, Oligomeric Mucus/Gel-Forming; High Molecular Weight Salivary Mucin MG1; Mucin 5, Subtype B, Tracheobronchial; Sublingual Gland Mucin; MUC-5B; MUC5; Mucin-5 Subtype B, Tracheobronchial;
- Gene ID
- 727897
- UniProt ID
- Q9HC84
- Long Name
- Mucin 5B, Oligomeric Mucus/Gel-Forming
- Function
- Signal transduction
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1263CT | Recombinant Mouse anti-Human MUC5B Monoclonal antibody (7G20-F5) | ELISA, WB | |
| VS3-FY988 | Recombinant Mouse Anti-MUC5B Antibody (clone 2A11G9) | ELISA, FC | Mouse IgG1 |
| VS3-FY989 | Recombinant Mouse Anti-MUC5B Antibody (clone 6H11B5) | ELISA, FC | Mouse IgG2b |
| VS7-0425-WR442 | Mouse Anti-MUC5B Recombinant Antibody (clone 7F5A1) | IHC, FC | Mouse IgG1 |
| VS7-0425-WR443 | Mouse Anti-MUC5B Recombinant Antibody (clone 6F8B2) | FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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