Rabbit Anti-NDUFC2 Recombinant Antibody (clone R05-2C2) (CAT#: VS3-FY1794)

This R05-2C2 recombinant monoclonal antibody has the ability to specifically bind to human NDUFC2. It is suitable for use in a variety of assays, including WB, IHC-P. This NDUFC2 antibody was verified by western blot analysis of NDUFC2 in Jurkat lysates.

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WB

Figure 1 Anti-NDUFC2 Antibody (VS3-FY1794) in WB.

Figure 1 Anti-NDUFC2 Antibody (VS3-FY1794) in WB.

The NDUFC2 expression in Jurkat lysates were detected using the anti-NDUFC2 by western blot assay.


Specifications

  • Immunogen
  • Recombinant human NDUFC2 protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human NDUFC2
  • Species Reactivity
  • Human
  • Clone
  • R05-2C2
  • Applications
  • Western Blot, Immunohistochemistry-Paraffin
  • MW
  • The calculated weight of the target protein is approximately 14 kDa, while the observed molecular weight stands at 14 kDa.
  • Related Disease
  • Mitochondrial Complex I Deficiency, Nuclear Type 36 and Mitochondrial Disease

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunohistochemistry: 1/50-1/100

Target

  • Alternative Names
  • NADH:Ubiquinone Oxidoreductase Subunit C2; NADH Dehydrogenase (Ubiquinone) 1, Subcomplex Unknown, 2, 14.5kDa; NADH-Ubiquinone Oxidoreductase Subunit B14.5b; Human Lung Cancer Oncogene 1 Protein; Complex I Subunit B14.5b; Complex I-B14.5b; CI-B14.5b
  • Sequence Similarities
  • Belongs to the complex I NDUFC2 subunit family.
  • Cellular Localization
  • Mitochondrion inner membrane
  • Post Translation Modifications
  • Ubiquitination at Lys106 and Lys114 (NX_O95298 [NX_O95298-1])
    Modification sites at PhosphoSitePlus (O95298)
  • Function
  • Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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