Rabbit Anti-NPR3 Recombinant Antibody (clone R05-2R6)
CAT#: VS3-XY3451
The product is a recombinant rabbit antibody that recognizes NPR3 (Natriuretic peptide receptor 3), which regulates diuresis, blood pressure and skeletal development. It is capable of binding to human, mouse and rat NPR3. It has been used in a variety of applications, such as Western Blot and Flow cytometry. The recommended dilutions of Western Blot and Flow cytometry is 1/500-1/1000 and 1/50-1/100, respectively.
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat NPR3
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R05-2R6
- Applications
- WB, FC
- Related Disease
- Boudin-Mortier Syndrome; Ischemic Colitis
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
FC: 1/50-1/100
Target
- Alternative Names
- NPRC; ANP-C; ANPRC; BOMOS; NPR-C; ANPR-C; GUCY2B; C5orf23
- Gene ID
- 4883
- UniProt ID
- P17342
- Long Name
- Natriuretic peptide receptor 3
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn293, Asn86, and Asn394 (NX_P17342 [NX_P17342-1])
Modification sites at PhosphoSitePlus (P17342)
Glycosylation from GlyGen (P17342) 5 sites, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001191304.1; NP_000899.1
- Function
- Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP.
May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects.
May regulate diuresis, blood pressure and skeletal development.
Does not have guanylate cyclase activity.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "NPR3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-CJ712 | Mouse Anti-NPR3 Recombinant Antibody (VS3-CJ712) | WB | Mouse IgG1, κ |
| VS3-FY2823 | Mouse Anti-NPR3 Recombinant Antibody (VS3-FY2823) | WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4930 | Anti-NPR3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4931 | Anti-Mouse NPR3 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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