Mouse Anti-OS Recombinant Antibody (clone TP-3) (CAT#: FAMAB-0080JF)

Recombinant mouse monoclonal antibody specially binds to osteosarcomas. This anti-osteosarcomas antibody TP-3 can be a promising tool for identification and subclassification of osteosarcomas.


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ELISA

Figure 1 ELISA measurements of the binding of serially diluted anti-OS monoclonal antibody.

Figure 1 ELISA measurements of the binding of serially diluted anti-OS monoclonal antibody.

The wells were reacted with NaBH4 and then with HRP-labeled goat anti-mouse IgG (whole; 1:2000).

Fujiwara, K., Yamamoto, Y., Saita, T., & Matsufuji, S. (2020). Metabolism and disposition of oseltamivir (OS) in rats, determined by immunohistochemistry with monospecific antibody for OS or its active metabolite oseltamivir carboxylate (OC): A possibility of transporters dividing the drugs’ excretion into the bile and kidney. Pharmacology Research & Perspectives, 8(3), e00597.

IHC

Figure 2 Immunostaining for OS in the liver of OS-administered rats.

Figure 2 Immunostaining for OS in the liver of OS-administered rats.

IHC for OS was carried out following digestion of sections with protease at 0.003% at 30°C for 30 minutes.

Fujiwara, K., Yamamoto, Y., Saita, T., & Matsufuji, S. (2020). Metabolism and disposition of oseltamivir (OS) in rats, determined by immunohistochemistry with monospecific antibody for OS or its active metabolite oseltamivir carboxylate (OC): A possibility of transporters dividing the drugs’ excretion into the bile and kidney. Pharmacology Research & Perspectives, 8(3), e00597.


Specifications

  • Immunogen
  • Tumor cells from a human osteosarcoma
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2b, κ
  • Specificity
  • Human osteosarcomas
  • Species Reactivity
  • Human
  • Clone
  • TP-3
  • Applications
  • ELISA, IHC
  • Related Disease
  • Osteosarcomas

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The OS antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunohistochemistry.

Target

  • Alternative Names
  • OS; Oteosarcomas

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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