AbPlus™ Anti-PRKCB Magnetic Beads (CBACN-451)

CAT#: VS-0424-XY217

The AbPlus Anti-PRKCB Magnetic Beads (CBACN-451) is an innovative affinity resin which is bound with anti-PRKCB specific antibody (CBACN-451). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PRKCB protein under native and denaturing conditions.

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magrose bead (> 50 μmol/mL gel)
  • Bead Ligand
  • Anti-PRKCB specific antibody (CBACN-451)
  • Target
  • PRKCB
  • Immunogen
  • Human PRKCB (aa 600-671)
  • Target Species
  • Human, Mouse, Rat
  • Antibody Clone
  • CBACN-451
  • Bead Capacity
  • 20-30 mg/mL binding antibody
  • Bead size
  • 10-37 μm
  • Stability
  • pH 2-14
  • Format
  • 20% Suspension
  • Buffer
  • PBS, pH 7.4, with 1% BSA
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
  • Alternative Names
  • PKCB; PRKCB1; PRKCB2; PKCI(2); PKCbeta; PKC-beta
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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