AbPlus™ Anti-STAP1 Magnetic Beads (VS-0724-YC386)

CAT#: VS-0724-YC386

The AbPlus Anti-STAP1 Magnetic Beads (VS-0724-YC386) is an innovative affinity resin which is bound with anti-STAP1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of STAP1 protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line A-431 Figure 2 RNA cell line category: Group enriched (Daudi, U-698)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-STAP1 specific antibody
  • Target
  • STAP1
  • Immunogen
  • Recombinant human STAP1 fragment derived from E. coli.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease.
  • Alternative Names
  • BRDG1; STAP-1
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