Rabbit Anti-TLN2 Recombinant Antibody (clone R02-9D2) (CAT#: VS3-XY3527)
The recombinant rabbit antibody is specific for TLN2 (Talin 2), which may play an important role in cell adhesion. The antibody specifically reacts with human, mouse and rat TLN2. It has been tested using Western Blot. The recommended dilutions of Western Blot is 1/500-1/1000.
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Custom Production
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17194/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17194/if_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54787/133851_B_8_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54787/133851_B_8_5.jpg
Figure 3 Kidney
(Proximal tubules (microvilli)
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54787/133851_A_7_5.jpg
(Proximal tubules (microvilli)
Staining: Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54787/133851_A_7_5.jpg
Figure 4 Testis
(Sertoli cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54787/133851_A_6_6.jpg
(Sertoli cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54787/133851_A_6_6.jpg
Figure 5 Heart
(Cardiomyocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54787/133851_B_6_6.jpg
(Cardiomyocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54787/133851_B_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, hTERT-HME1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171914-TLN2/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171914-TLN2/subcellular
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat TLN2
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R02-9D2
- Applications
- WB
- Related Disease
- Leukocyte Adhesion Deficiency, Type I; Leukocyte Adhesion Deficiency, Type Iii
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
Target
- Alternative Names
- ILWEQ
- Gene ID
- 83660
- UniProt ID
- Q9Y4G6
- Long Name
- Talin 2
- Cellular Localization
- Cytoplasm, Cell junction
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q9Y4G6)
Modification sites at neXtProt (NX_Q9Y4G6)
Glycosylation from GlyGen (Q9Y4G6) 3 sites, 1 O-linked glycan (3 sites)
- Protein Refseq
- NP_055874.2
- Function
- As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion.
Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity).
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1409CT | Recombinant Mouse anti-Mouse TLN2 Monoclonal antibody (79F8) | ELISA, ICC/IF, IHC-Fr, IP, WB |
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For Research Use Only. Not For Clinical Use.
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