Rabbit Anti-TRIM24 Recombinant Antibody (clone R09-3G6) (CAT#: VS3-FY1914)
This anti-TRIM24 antibody detected positive in western blot analysis of TRIM24 in K562, Hela lysates. The recombinant monoclonal antibody demonstrates high specificity in binding to human TRIM24. This R09-3G6 antibody is validated for western blot analysis of TRIM24 in K562, Hela lysates.
Specific Inquiry
WB
Figure 1 Anti-TRIM24 Antibody (VS3-FY1914) in WB.
The TRIM24 expression in K562, Hela lysates were detected using the anti-TRIM24 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human TRIM24
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human TRIM24
- Species Reactivity
- Human
- Clone
- R09-3G6
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 117 kDa, while the observed molecular weight stands at 117 kDa.
- Related Disease
- Differentiated Thyroid Carcinoma and Aortic Malignant Tumor
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Tripartite Motif Containing 24; RING-Type E3 Ubiquitin Transferase TIF1-Alpha; Transcriptional Intermediary Factor 1; E3 Ubiquitin-Protein Ligase TRIM24; RING Finger Protein 82; TIF1-Alpha; RNF82; TIF1A; TIF1; Transcription Intermediary Factor 1-Alpha
- Gene ID
- 8805
- UniProt ID
- O15164
- Cellular Localization
- Cytoplasm, Mitochondrion, Nucleus
- Post Translation Modifications
- Phosphorylated at Ser-768 by ATM kinase induces ubiquitination and degradation during DNA damage. (O15164-TIF1A_HUMAN)
Sumoylated. (O15164-TIF1A_HUMAN)
Undergoes ubiquitination-mediated degradation in response to DNA damage. (O15164-TIF1A_HUMAN)
Ubiquitination at Lys325, Lys341, and Lys458 (NX_O15164 [NX_O15164-1])
Modification sites at PhosphoSitePlus (O15164)
Glycosylation from GlyGen (O15164) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_024302749.1; XP_054215260.1; NP_003843.3; NP_056989.2
- Function
- Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes (By similarity).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "TRIM24"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2339MZ | Recombinant Mouse Anti-Human TRIM24 Antibody | IHC-P, WB | Mouse antibody |
| VS3-FY1487 | Recombinant Rabbit Anti-TRIM24 Antibody (clone R01-4B4) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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