Chicken Anti-VCTN1 Recombinant Antibody (clone S2) (CAT#: VS-0323-CJ1)

• Immunogen
• Recombinant B7-H4 protein (Phe29 to Ala258)

• Host Species
• Chicken

• Type
• Chicken IgY

• Specificity
• Human B7-H4

• Species Reactivity
• Human

• Clone
• S2

• Applications
• Enzyme-linked Immunosorbent Assay, Western Blot, Functional Assay

• Conjugate
• Unconjugated

• Related Disease
• Tumors

• Purity
• >95% as determined by SDS-PAGE

• Buffer
• PBS

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• ELISA: 0.05 mg/mL-0.1 mg/mL

• Alternative Names
• B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291

• Gene ID
• 79679

• UniProt ID
• Q7Z7D3

• Cellular Localization
• Cell membrane; Membrane

• Post Translation Modifications
• N-glycosylated.

• Protein Refseq
• NP_001240778.1; NP_001240779.1; NP_078902.2

• Function
• Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Isotype Control

• BRD-0674MZ
• Chicken IgY antibodies Isotype

• MOB-191CQ
• Chicken IgY Isotype Control Antibody

Secondary Antibody

• 2ND-006CQ
• Goat Anti-Chicken IgY (H&L) Antibody

• 2ND-007CQ
• Rabbit Anti-Chicken IgY (H&L) Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

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