H-2Db/Influenza A Polymerease PA (SCLENFRAYV) MHC Pentamer (CAT#: MHC-YF671)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Polymerease PA-derived peptide of SCLENFRAYV sequence covering 224-233 and H-2Db molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- H-2Db
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Polymerease PA
- Antigen Species
- Influenza A
- Peptide
- SCLENFRAYV
- Range
- 224-233
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
- Alternative Names
- Polymerase acidic protein; RNA-directed RNA polymerase subunit P2; PA
- Gene ID
- 956535
- UniProt ID
- P03433
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-099 | Mouse Anti-PA Recombinant Antibody (clone 14B7*) | Neut | Mouse IgG |
| PABZ-099 | Mouse Anti-PA Recombinant Antibody (clone 1H) | Neut | Mouse IgG |
| PABW-099 | Mouse Anti-PA Recombinant Antibody (clone M18) | Neut | Mouse IgG |
| HPAB-J0202-YC | Mouse Anti-PA Recombinant Antibody (HPAB-J0202-YC) | ELISA, Neut | Mouse IgG |
| HPAB-J0203-YC | Mouse Anti-PA Recombinant Antibody (HPAB-J0203-YC) | ELISA, Neut | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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