H-2Kd/HSV M105 (TYWPVVSDI) MHC Pentamer (CAT#: MHC-YF525)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed M105-derived peptide of TYWPVVSDI sequence covering 207-215 and H-2Kd molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.

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Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

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Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • H-2Kd
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • M105
  • Antigen Species
  • HSV
  • Peptide
  • TYWPVVSDI
  • Range
  • 207-215
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • Component of the helicase/primase complex. Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis. The primase synthesizes short RNA primers on the lagging strand that the polymerase elongates using dNTPs. Possesses helicase-like motifs and therefore may act as the helicase subunit of the complex.
  • Alternative Names
  • DNA replication helicase; M105, HELI

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