H2-Kd/HBV Large envelope (WYWGPSLYSI) MHC Pentamer (CAT#: MHC-YF510)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Large envelope-derived peptide of WYWGPSLYSI sequence covering 362-371 and H2-Kd molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


Specific Inquiry
  • Size:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • H2-Kd
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • Large envelope
  • Antigen Species
  • HBV
  • Peptide
  • WYWGPSLYSI
  • Range
  • 362-371
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane. In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein.
  • Alternative Names
  • Large envelope protein; L glycoprotein; L-HBsAg; Large S protein; Large surface protein;Major surface antigen

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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