Human Anti-Crf2 (clone MS112-IIB1) scFv-Fc Chimera (CAT#: VS-0325-FY171)

Anti-Crf2 scFv-Fc is a recombinant antibody designed for the specific detection of A. fumigatus. This antibody targets Crf2, a novel cell wall protein expressed by A. fumigatus during infection. The antibody is composed of a single-chain variable fragment (scFv) derived from either a human naive antibody library or a macaque immune library, fused to a human IgG1 Fc region. This design confers high specificity for A. fumigatus, enabling its use in various diagnostic applications such as immunofluorescence microscopy for direct visualization in tissue samples and ELISA for detection of Crf2 in serum. The Anti-Crf2 scFv-Fc antibody offers a promising new tool for the early and accurate diagnosis of invasive aspergillosis, particularly in immunocompromised individuals.

Specific Inquiry
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  • Datasheet
  • MSDS
  • COA

Specifications

  • Immunogen
  • Recombinant Crf2 protein.
  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Specificity
  • A. fumigatus Crf2
  • Species Reactivity
  • A. fumigatus
  • Clone
  • MS112-IIB1
  • Applications
  • Immunofluorescence, ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Aspergillus fumigatus Cell wall protein Crf2; Crf2
  • Long Name
  • Aspergillus fumigatus Cell wall protein Crf2
  • Function
  • Aspergillus fumigatus Crf2 is a cell wall protein that plays a role in fungal virulence and immune evasion. It contributes to the pathogenesis of aspergillosis and is a target for antifungal drug development.

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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