Recombinant Human Anti-KCNC3 Soluble TCR (MA3) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF1879)
Human TCR (MA3) recognizes KCNC3 peptide (FLPDLNVNA) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (MA3). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18041/ihc_selected.jpg
(Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18041/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18041/40717_B_9_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18041/40717_B_9_5.jpg
Figure 3 Cerebellum
(Purkinje cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18041/40717_B_9_8.jpg
(Purkinje cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18041/40717_B_9_8.jpg
Figure 4 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18041/40717_A_8_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18041/40717_A_8_3.jpg
Figure 5 RNA cell line category: Cell line enhanced (CACO-2, CAPAN-2, HDLM-2, HMC-1, K-562, SK-BR-3, T-47d, U-2 OS)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131398-KCNC3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131398-KCNC3
Specifications
- Host Species
- Human
- Target
- KCNC3
- Epitope
- FLPDLNVNA
- MHC
- HLA-A2
- Clone
- MA3
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Potassium Voltage-Gated Channel Subfamily C Member 3 variant FLP_A7V; FLPDLNVNA
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0091CT | Recombinant Mouse anti-Human KCNC3 Monoclonal antibody (EML440) | ICC/IF, WB |
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