Human Anti-MrkA scFv-Fc Chimera (VS-0325-FY205)
CAT#: VS-0325-FY205
This antibody targets MrkA, a major protein in the type III fimbriae complex of K. pneumoniae. It was generated using phage display and hybridoma platforms by screening for opsonophagocytic killing activity. The antibody binds to MrkA in a serotype-independent manner and has shown promising results in reducing biofilm formation and conferring protection in murine pneumonia models.
Specifications
- Immunogen
- Balb/c mice were immunized with 43816DM followed by a boost with a mixture of wild-type K. pneumoniae clinical isolates.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- K. pneumoniae MrkA
- Species Reactivity
- K. pneumoniae
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Klebsiella pneumoniae MrkA (major fimbrial adhesin); MrkA
- Long Name
- Klebsiella pneumoniae MrkA (major fimbrial adhesin)
- Function
- Klebsiella pneumoniae MrkA is a type 3 fimbrial adhesin that mediates bacterial attachment to host cells and contributes to biofilm formation. It plays a role in bacterial virulence and colonization.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "MrkA"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2423LY-F(E) | Human Anti-MrkA Recombinant Antibody (clone St1_C1); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-2424LY-F(E) | Human Anti-MrkA Recombinant Antibody (clone St2_C4); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-2425LY-F(E) | Human Anti-MrkA Recombinant Antibody (clone St3_C5); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-2426LY-F(E) | Human Anti-MrkA Recombinant Antibody (clone St4_C6); Fab Fragment | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2423LY | Human Anti-MrkA Recombinant Antibody (clone St1_C1) | ELISA, FC | Humanized IgG |
| HPAB-2424LY | Human Anti-MrkA Recombinant Antibody (clone St2_C4) | ELISA, FC | Humanized IgG |
| HPAB-2425LY | Human Anti-MrkA Recombinant Antibody (clone St3_C5) | ELISA, FC | Humanized IgG |
| HPAB-2426LY | Human Anti-MrkA Recombinant Antibody (clone St4_C6) | ELISA, FC | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2423LY-S(P) | Human Anti-MrkA Recombinant Antibody (clone St1_C1); scfv Fragment | ELISA, FC | Humanized scfv |
| HPAB-2424LY-S(P) | Human Anti-MrkA Recombinant Antibody (clone St2_C4); scfv Fragment | ELISA, FC | Humanized scfv |
| HPAB-2425LY-S(P) | Human Anti-MrkA Recombinant Antibody (clone St3_C5); scfv Fragment | ELISA, FC | Humanized scfv |
| HPAB-2426LY-S(P) | Human Anti-MrkA Recombinant Antibody (clone St4_C6); scfv Fragment | ELISA, FC | Humanized scfv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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