Recombinant Human Anti-SEC24A Soluble TCR (CE4) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2352)
Human TCR (CE4) recognizes SEC24A peptide (FLYNLLTRV) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (CE4). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli fibrillar center & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/56825/920_H7_11_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli fibrillar center & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/56825/920_H7_11_selected.jpg
Figure 2 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38901/ihc_selected.jpg
(Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38901/ihc_selected.jpg
Figure 3 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38901/82674_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38901/82674_A_8_5.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38901/82674_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38901/82674_A_8_8.jpg
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113615-SEC24A
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113615-SEC24A
Specifications
- Host Species
- Human
- Target
- SEC24A
- Epitope
- FLYNLLTRV
- MHC
- HLA-A2
- Clone
- CE4
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- SEC24A P469L; FLYNLLTRV
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6425 | Anti-SEC24A Immunohistochemistry Kit | IHC |
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