Recombinant Human Anti-TENM1 Soluble TCR (ZIP-Fos/ZIP-Jun) (VS-0622-YF2457) (CAT#: VS-0622-YF2457)
Human TCR recognizes TENM1 peptide (SANNIHFMRQSEIG) in the context of HLA-DRB1*15:01. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR. Please note that the activity is not guaranteed.

(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2848/ihc_selected.jpg

(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2848/8000_B_7_5.jpg

(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2848/8000_A_7_3.jpg

(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2848/8000_A_9_4.jpg

(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2848/8000_A_7_5.jpg

(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2848/8000_A_5_6.jpg

(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2848/8000_A_8_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000009694-TENM1
Specifications
- Host Species
- Human
- Target
- TENM1
- Species Reactivity
- Human
- Epitope
- SANNIHFMRQSEIG
- MHC
- HLA-DRB1*15:01
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Teneurin Transmembrane Protein 1; Protein Odd Oz/Ten-M Homolog 1; TEN-M1; Ten-1; ODZ1; TNM1; Odz, Odd Oz/Ten-M Homolog 1 (Drosophila); Odz (Odd Oz/Ten-M, Drosophila) Homolog 3; Odz, Odd Oz/Ten-M Homolog 1(Drosophila)
- Gene ID
- 10178
- UniProt ID
- Q9UKZ4
Downloads
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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