Recombinant Mouse Anti-EMC7 Soluble TCR (KIH) (VS-0622-YF5514) (CAT#: VS-0622-YF5514)
Mouse TCR recognizes EMC7 peptide (ALWGFFPVL) in the context of HLA-A2.1. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression

Figure 1 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong granular cytoplasmic positivity in leydig cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/ihc_selected.jpg
(Immunohistochemical staining of human testis shows strong granular cytoplasmic positivity in leydig cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/ihc_selected.jpg

Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_B_8_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_B_8_5.jpg

Figure 3 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_8_3.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_8_3.jpg

Figure 4 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_7_4.jpg
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_7_4.jpg

Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_7_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_7_5.jpg

Figure 6 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_6_6.jpg

Figure 7 Lymph node
(Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_8_8.jpg
(Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_8_8.jpg

Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134153-EMC7
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134153-EMC7
Specifications
- Host Species
- Mouse
- Target
- EMC7
- Species Reactivity
- Human
- Epitope
- ALWGFFPVL
- MHC
- HLA-A2.1
- Type
- Soluble TCR (KIH)
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- EMC7; HT022; C11orf3; C15orf24; ORF1-FL1; ER membrane protein complex subunit 7
- Gene ID
- 56851
- UniProt ID
- Q9NPA0
Downloads
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MHC Tetramers for Cancer
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC1088 | PE-A*02:01/Human EMC7 (ALWGFFPVL) MHC Tetramer | FCM | |
MHC-LC1089 | APC-A*02:01/Human EMC7 (ALWGFFPVL) MHC Tetramer | FCM | |
MHC-LC1090 | BV421-A*02:01/Human EMC7 (ALWGFFPVL) MHC Tetramer | FCM |
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