Recombinant Anti-BDKRB2 Vesicular Antibody, EV Displayed (VS-0425-YC575) (CAT#: VS-0425-YC575)
The Recombinant Anti-BDKRB2 Vesicular Antibody, EV Displayed (VS-0425-YC575) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to BDKRB2-expressed cells or tissues. BDKRB2 is a receptor for bradykinin, a peptide involved in vasodilation and pain response. This receptor associates with G proteins to stimulate a phosphatidylinositol-calcium messenger system, existing in two isoforms from alternative start codons.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3551/1876_D4_26_cr5b715fa48f144_selected.jpg
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3551/1876_D4_26_cr5b715fa48f144_selected.jpg
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/ihc_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/116237_B_8_5.jpg
(Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/116237_B_8_5.jpg
Figure 4 Caudate
(Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/116237_B_7_7.jpg
(Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/116237_B_7_7.jpg
Figure 5 RNA cell line category: Cell line enhanced (ASC TERT1, BJ hTERT+, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168398-BDKRB2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168398-BDKRB2
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- BDKRB2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse, Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Bradykinin receptor B2
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Vesicles, Plasma membrane, Cytokinetic bridge
- Introduction
- This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
- Alternative Names
- BK-2
- Gene ID
- 624
- UniProt ID
- P30411
Downloads
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See other products for "BDKRB2"
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Please select product type
Fab Antibodies
ScFv Antibodies
IgG Antibodies
Mouse Antibodies
Humanized Antibodies
Rabbit Monoclonal Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-106-F(E) | Recombinant Anti-human BDKRB2 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| MHH-106-F(E) | Recombinant Human Anti-human BDKRB2 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| HPAB-0360-YC-F(E) | Mouse Anti-BDKRB2 Recombinant Antibody; Fab Fragment (HPAB-0360-YC-F(E)) | ELISA, FuncS | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
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