Recombinant Anti-BDKRB2 Vesicular Antibody, EV Displayed (VS-0425-YC575)
CAT#: VS-0425-YC575
The Recombinant Anti-BDKRB2 Vesicular Antibody, EV Displayed (VS-0425-YC575) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to BDKRB2-expressed cells or tissues. BDKRB2 is a receptor for bradykinin, a peptide involved in vasodilation and pain response. This receptor associates with G proteins to stimulate a phosphatidylinositol-calcium messenger system, existing in two isoforms from alternative start codons.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line ASC TERT1
Immunofluorescent staining of human cell line ASC TERT1 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3551/1876_D4_26_cr5b715fa48f144_selected.jpg
Normal Tissue
Figure 2 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/116237_B_8_5.jpg
Normal Tissue
Figure 4 Caudate
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50841/116237_B_7_7.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (ASC TERT1, BJ hTERT+, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168398-BDKRB2
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- BDKRB2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse, Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Bradykinin receptor B2
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Vesicles, Plasma membrane, Cytokinetic bridge
- Introduction
- This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
- Alternative Names
- BK-2
- Gene ID
- 624
- UniProt ID
- P30411
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "BDKRB2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-106 | Recombinant Anti-human BDKRB2 Antibody | ELISA, WB, FC, FuncS | IgG |
| MHH-106 | Recombinant Human Anti-human BDKRB2 Antibody | RIA, IF, FuncS | IgG |
| MOB-0466MZ | Mouse Anti-BDKRB2 Recombinant Antibody (clone 3F6) | WB | Mouse IgG1 |
| HPAB-0360-YC | Mouse Anti-BDKRB2 Recombinant Antibody (HPAB-0360-YC) | ELISA, FuncS | Mouse IgG |
| MRO-0165-CN | Rabbit Anti-BDKRB2 Recombinant Antibody (clone JU39-04) | WB, FC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-106-F(E) | Recombinant Anti-human BDKRB2 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| MHH-106-F(E) | Recombinant Human Anti-human BDKRB2 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| HPAB-0360-YC-F(E) | Mouse Anti-BDKRB2 Recombinant Antibody; Fab Fragment (HPAB-0360-YC-F(E)) | ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-106-S(P) | Recombinant Anti-human BDKRB2 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| MHH-106-S(P) | Recombinant Human Anti-human BDKRB2 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| HPAB-0361-YC-S(P) | Human Anti-BDKRB2 Recombinant Antibody; scFv Fragment (HPAB-0361-YC-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1265CL | Anti-Human BDKRB2 Recombinant Antibody (H1/L1) | FuncS | Humanized antibody |
| TAB-1266CL | Anti-Human BDKRB2 Recombinant Antibody (H2/L2) | FuncS | Humanized antibody |
| TAB-1267CL | Anti-Human BDKRB2 Recombinant Antibody (H37/L37) | FuncS | Humanized antibody |
| TAB-1268CL | Anti-Human BDKRB2 Recombinant Antibody (H38/L38) | FuncS | Humanized antibody |
| TAB-1269CL | Anti-Human BDKRB2 Recombinant Antibody (H39/L39) | FuncS | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0350 | Hi-Affi™ Rabbit Anti-BDKRB2 Recombinant Antibody (clone DS350AB) | WB, IP, FC | Rabbit IgG |
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