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αVβ3
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- Human Anti-αVβ3 Recombinant Antibody (TAB-0358CL) (TAB-0358CL)
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- Species Reactivity: Cross-react with mouse and rat (VPI-2690B had a higher affinity for human than mouse but equal affinity for human and rat peptide sequences)
- Type: Humanized Antibody
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- Human Anti-αVβ3 Recombinant Antibody (TAB-0359CL) (TAB-0359CL)
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- Type: Humanized Antibody
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- Human Anti-αVβ3 Recombinant Antibody (TAB-0360CL) (TAB-0360CL)
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- Type: Humanized Antibody
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- Human Anti-αVβ3 Recombinant Antibody scFv Fragment (TAB-0358CL-S(P)) (TAB-0358CL-S(P))
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- Species Reactivity: Cross-react with mouse and rat (VPI-2690B had a higher affinity for human than mouse but equal affinity for human and rat peptide sequences)
- Type: Humanized Antibody
Compare
- Human Anti-αVβ3 Recombinant Antibody scFv Fragment (TAB-0359CL-S(P)) (TAB-0359CL-S(P))
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- Type: Humanized Antibody
Compare
- Human Anti-αVβ3 Recombinant Antibody scFv Fragment (TAB-0360CL-S(P)) (TAB-0360CL-S(P))
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- Type: Humanized Antibody
Compare
- Human Anti-αVβ3 Recombinant Antibody Fab Fragment (TAB-0358CL-F(E)) (TAB-0358CL-F(E))
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- Species Reactivity: Cross-react with mouse and rat (VPI-2690B had a higher affinity for human than mouse but equal affinity for human and rat peptide sequences)
- Type: Humanized Antibody
Compare
- Human Anti-αVβ3 Recombinant Antibody Fab Fragment (TAB-0359CL-F(E)) (TAB-0359CL-F(E))
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- Type: Humanized Antibody
Compare
- Human Anti-αVβ3 Recombinant Antibody Fab Fragment (TAB-0360CL-F(E)) (TAB-0360CL-F(E))
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- Type: Humanized Antibody
Compare
- Human Anti-αVβ3 Recombinant Antibody, mRNA (TAB-0358CL-mRNA) (TAB-0358CL-mRNA)
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- Species Reactivity: Human, Mouse, Rat
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- Human Anti-αVβ3 Recombinant Antibody, mRNA (TAB-0359CL-mRNA) (TAB-0359CL-mRNA)
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- Human Anti-αVβ3 Recombinant Antibody, mRNA (TAB-0360CL-mRNA) (TAB-0360CL-mRNA)
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For Research Use Only. Not For Clinical Use.
αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed by platelets. Furthermore, it is a receptor for phagocytosis on macrophages or dendritic cells. Integrin αVβ3 is potential drug target because abnormal expression of v3 is linked to the development and progression of various diseases.
Inhibitors like etaracizumab may be used as antiangiogenics.
Inhibitors like etaracizumab may be used as antiangiogenics.