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αVβ3
αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed by platelets. Furthermore, it is a receptor for phagocytosis on macrophages or dendritic cells. Integrin αVβ3 is potential drug target because abnormal expression of v3 is linked to the development and progression of various diseases.
Inhibitors like etaracizumab may be used as antiangiogenics.
Inhibitors like etaracizumab may be used as antiangiogenics.
- Human Anti-αVβ3 Antibody (clone VH5/Vκ2), mRNA (TAB-0360CL-mRNA)
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- Human Anti-αVβ3 Antibody (clone VH4/Vκ1), mRNA (TAB-0359CL-mRNA)
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- Anti-αVβ3 Recombinant Antibody Fab Fragment (VH5/Vκ2) (TAB-0360CL-F(E))
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- Type: Humanized Antibody
- Anti-αVβ3 Recombinant Antibody Fab Fragment (VH4/Vκ1) (TAB-0359CL-F(E))
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- Type: Humanized Antibody
- Anti-αVβ3 Recombinant Antibody Fab Fragment (VPI-2690B) (TAB-0358CL-F(E))
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- Species Reactivity: Cross-react with mouse and rat (VPI-2690B had a higher affinity for human than mouse but equal affinity for human and rat peptide sequences)
- Type: Humanized Antibody
- Anti-αVβ3 Recombinant Antibody (VH5/Vκ2) (TAB-0360CL)
-
- Type: Humanized Antibody
- Anti-αVβ3 Recombinant Antibody (VH4/Vκ1) (TAB-0359CL)
-
- Type: Humanized Antibody
- Anti-αVβ3 Recombinant Antibody (VPI-2690B) (TAB-0358CL)
-
- Species Reactivity: Cross-react with mouse and rat (VPI-2690B had a higher affinity for human than mouse but equal affinity for human and rat peptide sequences)
- Type: Humanized Antibody
- Human Anti-αVβ3 Antibody (clone VPI-2690B), mRNA (TAB-0358CL-mRNA)
-
- Species Reactivity: Human, Mouse, Rat
- Anti-αVβ3 Recombinant Antibody scFv Fragment (VH5/Vκ2) (TAB-0360CL-S(P))
-
- Type: Humanized Antibody
- Anti-αVβ3 Recombinant Antibody scFv Fragment (VH4/Vκ1) (TAB-0359CL-S(P))
-
- Type: Humanized Antibody
- Anti-αVβ3 Recombinant Antibody scFv Fragment (VPI-2690B) (TAB-0358CL-S(P))
-
- Species Reactivity: Cross-react with mouse and rat (VPI-2690B had a higher affinity for human than mouse but equal affinity for human and rat peptide sequences)
- Type: Humanized Antibody
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For Research Use Only. Not For Clinical Use.