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ABRA

Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
Predicted location

Intracellular

Single cell type specificity

Group enriched (Cardiomyocytes, Early spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Binds F-actin and ABLIM1, ABLIM2 AND ABLIM3. Interaction with ABLIM2 AND ABLIM3 enhances activity (By similarity).

Molecular function

Actin-binding, Activator

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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