ABRA

Anti-ABRA Products

Mouse Anti-ABRA Recombinant Antibody (clone 35B6) (MOB-3516z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, IP, IF, ELISA
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For Research Use Only. Not For Clinical Use.

Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.

Predicted location

Intracellular

Single cell type specificity

Group enriched (Cardiomyocytes, Early spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Binds F-actin and ABLIM1, ABLIM2 AND ABLIM3. Interaction with ABLIM2 AND ABLIM3 enhances activity (By similarity).

Molecular function

Actin-binding, Activator

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