Loading...
AFAP1
The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.
Predicted location
Intracellular
Single cell type specificity
Group enriched (Late spermatids, Early spermatids, Oligodendrocyte precursor cells, Inhibitory neurons, Extravillous trophoblasts)
Immune cell specificity
Immune cell enhanced (eosinophil)
Cell line specificity
Cell line enhanced (TIME)
Interaction
Monomer and homomultimer. Interacts via its C-terminus with F-actin; probably involving AFAP1 multimers (By similarity). Interacts with activated SRC SH3-SH2 domains. Interacts via its PH 1 domain with PRKCA, PRKCB and PRKCI (By similarity).
Molecular function
Actin-binding
More Types Infomation
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.