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AGRP

Anti-AGRP Products

Mouse Anti-AGRP Recombinant Antibody (clone 35H4) (MOB-2950z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
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Mouse Anti-AGRP Recombinant Antibody (clone NN0096-43C23) (MOB-0503MZ)
- Species Reactivity: Human
- Type: Mouse IgG2
- Application: WB
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Anti-AGRP Immunohistochemistry Kit (VS-0525-XY224)
- Species Reactivity: Human
- Target: AGRP
- Application: IHC
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For Research Use Only. Not For Clinical Use.

This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

Protein class

Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Hofbauer cells, Theca cells, Macrophages, Distal tubular cells, Leydig cells, Peritubular cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (CACO-2)

Interaction

Interacts with melanocortin receptors MC3R, MC4R and MC5R.

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