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ALOX12
Loading...Anti-ALOX12 Products
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- Derivation: Phage display library screening
- Species Reactivity: Human, Does not react with Mouse
- Type: Rabbit IgG
- Application: WB
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- Anti-ALOX12 Immunohistochemistry Kit (VS-0525-XY322)
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- Species Reactivity: Human
- Target: ALOX12
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
Protein class
Disease related genes, Enzymes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Macrophages)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Group enriched (A-431, HEL)
Molecular function
Dioxygenase, Hydrolase, Oxidoreductase
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