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AMPK-ACC Pathway

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For Research Use Only. Not For Clinical Use.


Background

The AMPK-ACC pathway represents a central axis in cellular energy homeostasis, playing a pivotal role in sensing the cell's metabolic state and coordinating adaptive responses. At its core is AMP-activated protein kinase (AMPK), a highly conserved serine/threonine kinase that functions as a master metabolic regulator, often referred to as the "cellular fuel gauge." AMPK is activated when cellular energy levels are low, indicated by an increased AMP:ATP or ADP:ATP ratio.
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