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APBB2
Loading...Anti-APBB2 Products
- Human Anti-APBB2 Recombinant Soluble TCR (clone FF1) (scTCR-0097YC-S(P))
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- Species Reactivity: Human
- Epitope: VQYLGMLPV
- MHC: HLA-A2
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- Human Anti-APBB2 Recombinant Soluble TCR (clone GH11) (scTCR-0098YC-S(P))
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- Species Reactivity: Human
- Epitope: VQYLGMLPV
- MHC: HLA-A2
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- Recombinant Human Anti-APBB2 Soluble TCR (FF1) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1398)
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- Species Reactivity: Human
- Epitope: VQYLGMLPV
- MHC: HLA-A2
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- Recombinant Human Anti-APBB2 Soluble TCR (GH11) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1399)
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- Species Reactivity: Human
- Epitope: VQYLGMLPV
- MHC: HLA-A2
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- Recombinant Human Anti-APBB2 Soluble TCR (FF1) (C-Cys) (VS-0622-YF4106)
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- Species Reactivity: Human
- Epitope: VQYLGMLPV
- MHC: HLA-A2
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- Recombinant Human Anti-APBB2 Soluble TCR (GH11) (C-Cys) (VS-0622-YF4107)
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- Species Reactivity: Human
- Epitope: VQYLGMLPV
- MHC: HLA-A2
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- Recombinant Human Anti-APBB2 Soluble TCR (FF1) (KIH) (VS-0622-YF6814)
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- Species Reactivity: Human
- Epitope: VQYLGMLPV
- MHC: HLA-A2
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- Recombinant Human Anti-APBB2 Soluble TCR (GH11) (KIH) (VS-0622-YF6815)
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- Species Reactivity: Human
- Epitope: VQYLGMLPV
- MHC: HLA-A2
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Predicted location
Intracellular
Single cell type specificity
Group enriched (Oligodendrocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Immune cell enriched (naive B-cell)
Cell line specificity
Cell line enhanced (HUVEC TERT2, TIME)
Interaction
Interacts (via C-terminus) with APP (via C-terminus) (PubMed:8855266, PubMed:14527950). Interacts with APLP2 (via cytoplasmic domain) (PubMed:8855266).
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