Recombinant Human Anti-APBB2 Soluble TCR (GH11) (C-Cys)
CAT#: VS-0622-YF4107
Human TCR (GH11) recognizes APBB2 peptide (VQYLGMLPV) in the context of HLA-A2. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23542/196_A2_2_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23542/52510_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23542/52510_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23542/52510_A_8_4.jpg
Normal Tissue
Figure 5 Pancreas
Exocrine glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23542/52510_A_2_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23542/52510_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23542/52510_A_4_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/23542/52510_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163697-APBB2
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Specifications
- Host Species
- Human
- Target
- APBB2
- Species Reactivity
- Human
- Epitope
- VQYLGMLPV
- MHC
- HLA-A2
- Clone
- GH11
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Alzheimer's disease
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Amyloid Beta Precursor Protein Binding Family B Member 2; Protein Fe65-Like 1; FE65L1; FE65L; Amyloid Beta (A4) Precursor Protein-Binding, Family B, Member 2; Amyloid Beta A4 Precursor Protein-Binding Family B Member 2; Amyloid-Beta A4 Precursor Protein-Binding Family B Member 2; Fe65-Like 1; Fe65-Like;
- Gene ID
- 323
- UniProt ID
- Q92870
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